师资队伍

周树堂

   周树堂,博士,教授,博士生导师。2002年毕业于加拿大皇后大学,获生物化学与分子生物学博士学位。2003-2004年在皇后大学蛋白质功能中心和生物化学系从事博士后研究,2005年起在美国杜克大学任助理研究员、助理教授。2009年入选中国科学院“百人计划”,2010年始担任中科院动物研究所研究员、博士生导师、研究组长,2011年获“百人计划”择优支持。2012年获美国PRS Young Investigator Award。2015年2月被聘为河南大学“攀登计划”特聘教授。
   长期从事昆虫生殖发育调控和植物保护研究,近年的研究成果发表在PNAS,PLoS Genetics,Insect Biochemistry and Molecular Biology,Insect Molecular Biology等国际知名SCI期刊,被 Faculty of 1000推荐。出版专著1部,授权专利3项。
   目前主持参加国家自然科学基金、973课题等,担任中国昆虫学会理事,基因组专业委员会委员,发育与遗传专业委员会副主任,《昆虫学报》、Journal of Allergy and Therapy编委。

研究领域
  生长发育快、繁殖量大、蜕皮变态是昆虫的重要特征。快速生长发育导致大量取食,繁殖量大能使种群数量迅速增加,通过蜕皮使个体迅速增大,通过变态获得飞翔和生殖能力,从而扩大了生活范围,增强了适应能力,增加了害虫危害植物的程度。昆虫发育与生殖是机体内分泌调节和基因相互作用的复杂生物学过程,与植物和环境等因子密切关联。
研究团队综合运用组学、分子生物学、生物信息学、细胞生物学、遗传学等手段,研究昆虫生殖与发育的分子机制,昆虫与植物的互作,以及昆虫对逆境应激的分子机理。

代表性论文(*指通讯作者)
1. Guo W, Wu Z, Song J. Jiang F, Deng S, Walker VK, Zhou S*. 2014. Juvenile hormone-receptor complex acts on Mcm4 and Mcm7 to promote polyploidy and vitellogenesis in the migratory locust.PLoS Genetics. 10(10): e1004702.
2. Song J, Wu Z, Wang Z, Deng S, Zhou S*. 2014. Krüppel-homolog 1 mediates juvenile hormone action to promote vitellogenesis and oocyte maturation in the migratory locust. Insect Biochem Mol Biol. 52: 94-101.
3. Ren D, Cai Z, Song J, Wu Z, Zhou S*. 2014. dsRNA uptake and persistence account for tissue-dependent susceptibility to RNA interference in the migratory locust, Locusta migratoria. Insect Mol Biol. 23(2): 175–184.
4. Liu L, Zheng H, Jiang F, Guo W, Zhou S*. 2014. Comparative transcriptional analysis of asexual and sexual morphs reveals possible mechanisms in reproductive polyphenism of the cotton aphid.PLoS ONE. 9(6): e99506.
5.Song J, Guo W, Jiang F, Kang L, Zhou S*. 2013. Argonaute 1 is indispensable for juvenile hormone mediated oogenesis in the migratory locust, Locusta migratoria. Insect Biochem Mol Biol.43(9): 879-887.
6. Zhou S*, Nissao E, Jackson IL, Leong W, Dancy L, Cuttitta F, Vujaskovic Z, Sunday ME*. Radiation-induced lung injury is mitigated by blockade of gastrin-releasing peptide. Am J Pathol. 2013. 182(4):1248-1254.
7. Zhou S, Degan S, Potts EN, Foster FM, Sunday ME. 2009. NPAS3 is a trachealess homolog critical for lung development and homeostasis. Proc Natl Acad Sci USA. 106(28), 11699-11704. Recommended by “Faculty of 1000”.
8. Levesque BM#, Zhou S#, Shan L, Kong Y, Sunday ME. 2007. NPAS1 regulates branching morphogenesis in embryonic lung. Am J Respir Cell Mol Biol. 36(4), 427-434. #Co-first authors.
9. Zhou S, Tejada M, Wyatt GR, Walker VK. 2006. A DNA-binding protein, tfp1, involved in juvenile hormone-regulated gene expression in Locusta migratoria. Insect Biochem Mol Biol. 36: 724-734.
10.Zhou S, Webb BA, Eves R, Mak AS. 2006. Effects of tyrosine phosphorylation of cortactin on podosome formation in A7r5 vascular smooth muscle cells. Am J Physiol Cell Physiol. 290, C463-471.
11.Webb BA, Zhou S, Eves R, Shen L, Jia L, Mak AS. 2006. Phosphorylation of cortactin by p21-activated kinase. Arch Biochem Biophys. 456, 183-193.
12.Eves R, Webb BA, Zhou S, Mak AS. 2006. Caldesmon is an integral component of podosomes in smooth muscle cells. J Cell Sci. 119, 1691-1702.
13.Webb BA, Eves R, Crawley SW, Zhou S, Côté GP, Mak AS. 2005. PAK1 induces podosome formation in A7r5 vascular smooth muscle cells in a PAK-interacting exchange factor-dependent manner. Am J Physiol Cell Physiol. 289: C898-907.
14.Hayward DC, Dhadialla TS, Zhou S, Kuiper MJ, Ball EE, Wyatt GR, Walker VK. 2003. Ligand specificity and developmental expression of RXR and ecdysone receptor in the migratory locust. J Insect Physiol. 49, 1135-1144.
15.Zhou S, Zhang J, Hirai M, Chinzei Y, Kayser H, Wyatt GR, Walker VK. 2002. A DNA-binding protein involved in gene regulation by juvenile hormone. Mol Cell Endocrinol. 190, 177-185.
16.Zhou S, Zhang J, Fam MD, Wyatt GR, Walker VK. 2002. Sequences of elongation factors-1a and -1g and stimulation by juvenile hormone in Locusta migratoria. Insect Biochem Mol Biol. 32, 1567-1576.
17.赵连丰, 宋佳晟, 周树堂*. 2015. MicroRNA在昆虫变态及生殖过程中的调控作用. 昆虫学报. 58 (1): 90-98.
18.周树堂*,郭伟,宋佳晟. 2012. 保幼激素的分子作用机制研究. 应用昆虫学报. 49 (5): 1087-1094.
19.周树堂*,郭伟,宋佳晟. 2012. 昆虫变态的激素与基因调控. 生物学通报. 47: 1-6.

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E-mail:szhou@henu.edu.cn