教师名录

【研究方向】藻类生物学、光合作用环境胁迫响应、生物合成与绿色生物制造。以光合作用研究模式材料蓝细菌和小球藻为研究对象，立足光合作用与绿色生物制造，聚焦环境问题，围绕微藻环境适应、生物能源与生物减排等科学问题，开展系统性研究。

【办公地点】作物国重402室

【联系邮箱】wangqiang@henu.edu.cn

【教育及工作经历】

2002年在中国科学院北京植物研究所获得博士学位

2002年10月至2010年7月期间先后在以色列希伯来大学、美国田纳西大学、阿肯色大学和密西根州立大学从事独立研究工作。

2011年获中国科学院“百人计划”择优资助，入职中科院水生生物研究所。

2019年1月入选河南大学“杰出人才特区支持计划”特聘教授。

【代表性论文】

1.Ugya A.Y., Chen H, Wang Q. Microalgae biofilm carbon and nitrogen sequestration as a tool for economic and environmental sustainability. Critical Reviews In Environmental Science And Technology. 2023. DOI: 10.1080/10643389.2023.2209492.

2.Ugya, A.Y., Chen, H., Wang, Q. Microalgae biofilm system as an efficient tool for wastewater remediation and potential bioresources for pharmaceutical product production: an overview. International Journal of Phytoremediation, .2023,1-12.

3.Ugya, Y.A., Chen, H., Sheng, Y., Ajibade, F.O., Wang, Q. A review of microalgae biofilm as an eco-friendly approach to bioplastics, promoting environmental sustainability. Environmental Research, 2023, 236, 116833.

4.Chen WX, Li TP, Du SW, Chen H, Wang Q. Microalgal polyunsaturated fatty acids: Hotspots and production techniques. Frontiers In Bioengineering And Biotechnology. 2023, 11, 1146881.

5.Li X, Hou WW, Lei JX, Chen H, Wang Q. The Unique Light-Harvesting System of the Algal Phycobilisome: Structure, Assembly Components, and Functions. International Journal of Molecular Sciences. 2023, 24(11), 9733.

6.Zheng, S., A. Wu, H. Wang, L. Chen, J. Song, H. Zhang, M. He, C. Wang, H. Chen, and Q. Wang, Purification efficiency of Pyropia-processing wastewater and microalgal biomass production by the combination of Chlorella sp. C2 cultivated at different culture temperatures and chitosan. Bioresource Technology, 2023:128730.

7.Zheng, Y., C. Xue, H. Chen, A. Jia, L. Zhao, J. Zhang, L. Zhang, and Q. Wang, Reconstitution and expression of mcy gene cluster in the model cyanobacterium Synechococcus 7942 reveals a role of MC-LR in cell division. New Phytol, 2023. 238(3), 1101-1114.

8.Zheng, S., S. Chen, A. Wu, H. Wang, S. Sun, M. He, C. Wang, H. Chen, and Q. Wang, Efficient nutrient removal of Pyropia-processing wastewater and rapid algal biomass harvesting by Scenedesmus obliquus combined with chitosan. Journal of Water Process Engineering, 2023. 51: 103365.

9.Sun, Z., H. Chen, L. Sun, and Q. Wang, Converting carbon dioxide to high value-added products: Microalgae-based green biomanufacturing. GCB Bioenergy, 2023. 21.249.

10.Hu, X., Y. Fan, C. Mao, H. Chen, and Q. Wang, Application of transposon insertion site sequencing method in the exploration of gene function in microalgae. Frontiers in Microbiology, 2023. 14.

11.Hu, J., D. Wang, H. Chen, and Q. Wang, Advances in Genetic Engineering in Improving Photosynthesis and Microalgal Productivity. International Journal of Molecular Sciences, 2023. 24(3): p. 1898.

12.Chen, W., T. Li, Y. Ren, J. Wang, H. Chen, and Q. Wang, Biological hydrogen with industrial potential: Improvement and prospection in biohydrogen production. Journal of Cleaner Production, 2023. 387: p. 135777.

13.刘赞，孙中亮，史良，王强.黄河流域微塑料污染现状及防治策略.生物工程学报, 2023. 1-14.

14.Zheng, S., S. Zou, H. Wang, T. Feng, S. Sun, H. Chen, and Q. Wang, Reducing culture medium nitrogen supply coupled with replenishing carbon nutrient simultaneously enhances the biomass and lipid production of Chlamydomonas reinhardtii. Frontiers in Microbiology, 2022. 13.

15.Zheng, S., S. Zou, T. Feng, S. Sun, X. Guo, M. He, C. Wang, H. Chen, and Q. Wang, Low temperature combined with high inoculum density improves alpha-linolenic acid production and biochemical characteristics of Chlamydomonas reinhardtii. Bioresour Technol, 2022. 348: p. 126746.

16.Li, X., C. Xue, H. Chen, H. Zhang, and Q. Wang, Small antisense RNA ThfR positively regulates Thf1 in Synechocystis sp. PCC 6803. Journal of Plant Physiology, 2022. 271: p. 153642.

17.Dai, N., Q. Wang, B. Xu, and H. Chen, Remarkable Natural Biological Resource of Algae for Medical Applications. Frontiers in Marine Science, 2022. 9.

18.Chen, H. and Q. Wang, Microalgae-Based Green Bio-Manufacturing—How Far From Us. Frontiers in Microbiology, 2022. 13.

19.孙中亮,陈辉,王强,从CO2到有机物—碳中和的微藻绿色生物制造.合成生物学, 2022, 1-13.

20.Chen H., Li K., Xue C., Wang Q. A Novel Method for Non-invasive Estimation of Primary Productivity in Aquatic Ecosystems Using a Chlorophyll Fluorescence-Induced Dynamic Curve. Frontiers in Microbiology, 2021, 12: 682250.

21.Chen H., Wang Q. Regulatory mechanisms of lipid biosynthesis in microalgae [J]. Biological Reviews, 2021, 96(5): 2373-2391.

22.Chen H., Wang Q. Microalgae-Based Green Bio-Manufacturing-How Far From Us [J]. Journal, 2022, 13(Issue): 832097.

23.Jia A., Zheng Y., Chen H., Wang Q. Regulation and Functional Complexity of the Chlorophyll-Binding Protein IsiA [J]. Frontiers in Microbiology, 2021, 12: 774107-774107.

24.Li X., Xue C., Chen H., Zhang H., Wang Q. Small antisense RNA ThfR positively regulates Thf1 in Synechocystis sp. PCC 6803. Journal of Plant Physiology, 2022, 271: 153642.

25.Zheng Y., Xue C., Chen H., He C., Wang Q. Low-temperature adaptation of the snow alga Chlamydomonas nivalis is associated with the photosynthetic system regulatory process. Frontiers in Microbiology, 2020, 11: 1233.

26.Zhou C., Chen H., Zhao H., Wang Q. Microcystin biosynthesis and toxic effects. Algal Research-Biomass Biofuels and Bioproducts, 2021, 55: 102277.

27.Li, T., Jiang, Q., Huang, J., Aitchison, C.M., Huang, F., Yang, M., Dykes, G.F., He, H.L., Wang, Q., Sprick, R.S. Reprogramming bacterial protein organelles as a nanoreactor for hydrogen production. Nature Communications, 2020, 11:5448.

28.Zhao, L.-S., Huokko, T., Wilson, S., Simpson, D.M., Wang, Q., Ruban, A.V., Mullineaux, C.W., Zhang, Y.-Z., Liu, L.-N. Structural variability, coordination and adaptation of a native photosynthetic machinery. Nature Plants, 2020, 6(7): 869-882.

29.Zheng, S., Chen, S., Zou, S., Yan, Y., Gao, G., He, M., Wang, C., Chen, H., Wang, Q. Bioremediation of Pyropia-processing wastewater coupled with lipid production using Chlorella sp. Bioresource Technology, 2021, 321.

30.Zhang, X., Chen, H., Wang, H., Wang, Q. Time-course effects of Tris(1,3-dichloro-2-propyl) phosphate (TDCPP) on Chlorella pyrenoidosa: Growth inhibition and adaptability mechanisms. Journal of Hazardous Materials, 2021, 402: 123784.

31.Wang Q. Microbial Photosynthesis, Springer Nature, 2020；

32.Chen, H., Wang, X., and Wang, Q. Microalgal biofuels in China: The past, progress and prospects. Global Change Biology Bioenergy. 2020, 12: 1044-1065;

33.Chen, H., and Wang, Q. Microalgae-based nitrogen bioremediation. Algal Research 2020, 46:101775;

34.Calzadilla, P.I., Zhan, J., Sétif, P., Lemaire, C., Solymosi, D., Battchikova, N., Wang, Q., and Kirilovsky, D. The cytochrome b6f complex is not involved in cyanobacterial state transitions. The Plant Cell, 2019, 31, 911-931;

35.Wang J, Zhou W, Chen H, Zhan J, He C and Wang Q. Ammonium Nitrogen Tolerant Chlorella Strain Screening and Its Damaging Effects on Photosynthesis. Front. Microbiol. 2019, 9:3250. doi: 10.3389/fmicb.2018.03250

36.Chen, H., Li, T., and Wang, Q. Ten years of algal biofuel and bioproducts: gains and pains. Planta, 2019, 249:195-219；

37.Zhan, J., and Wang, Q. Photoresponse Mechanism in Cyanobacteria: Key Factor in Photoautotrophic Chassis, in Synthetic Biology of Cyanobacteria, eds. W. Zhang & X. Song. (Singapore: Springer Singapore), 2018, 75-96.

38.Hu, J., Zhan, J., Chen, H., He, C., Cang, H., and Wang, Q. (2018). The Small Regulatory Antisense RNA PilR Affects Pilus Formation and Cell Motility by Negatively Regulating pilA11 in Synechocystis sp. PCC 6803. Frontiers in Microbiology, 2018, 9(786).

39.Hu, J., and Wang, Q. (2018). Regulatory sRNAs in Cyanobacteria. Frontiers in Microbiology, 2018, 9(2399).

40.Chen, H., and Wang, Q. Ten years of microalgal biofuels in environmental applications. Science Foundation in China 2018, 26(3), 69-80.

41.Giordano M, Wang Q. Microalgae for Industrial Purposes. In: Vaz Jr S, (ed). Biomass and Green Chemistry: Building a Renewable Pathway. Cham: Springer Nature Publishing, 2018, 133-167

42.Chen H, Wang J, Zheng Y, Zhan J, He C, Wang Q. Algal biofuel production coupled bioremediation of biomass power plant wastes based on Chlorella sp. C2 cultivation. Applied Energy, 2018, 211: 296-305

43.Ma F, Zhang X, Zhu X, Li T, Zhan J, Chen H, He C, Wang Q. Dynamic Changes of IsiA-Containing Complexes during Long-Term Iron Deficiency in Synechocystis sp. PCC 6803. Mol Plant, 2017, 10(1): 143-154

【项目】

1.国家重点研发计划“合成生物学”重点专项：微藻底盘细胞的理性设计与系统改造，2021-2026，经费总额1949万元，主持；

2.国家基金面上项目：Slr1970负调控Synechocystis 6803强光胁迫响应的新机制，2022-2025，经费总额58万元，主持；

3.河南省高校科技创新团队：光合成生物学，2022-2024，经费总额50万元，主持；

4.国家重点研发计划“合成生物学”重点专项子课题，抗光氧化运行模块/基因线路的设计、组装和优化，2020-2025，152万元，主持；

5.973计划课题，微藻用于炼油过程CO2减排的工程基础，2012-2017，256万元，主持；

6.973计划课题，能源微藻优良藻种的遗传改造，2011-2015，50万元，主持；

7.国家自然科学基金重大研究计划项目，水圈碳循环原驱动力——水体初级生产力的原位无损分析方法的建立与应用，2019-2021，直接经费80万元，主持；

8.国家自然科学基金面上项目，Synechocystis PCC 6803缺铁诱导蛋白IsiA相互作用网络的构建及其功能研究，2013-2016，80万元，主持；

9.国家自然科学基金面上项目，蓝细菌Synechocystis sp. PCC 6803非编码反义RNA ThfR的功能及其调控机制研究，2018-2021，直接经费65万元，主持；

10.科技部设备研制项目，水生态系统活力分析仪，2018-2019，296万元，主持；

11.湖北省自然科学基金重点项目，能源微藻用于去除工业烟气中氮氧化物(NOx)的研究，2013-2015，10万元，主持；

12.湖北省自然科学基金创新群体项目，微藻固炭脱硝机理及高附加值产物的提取工艺，2017-2020，50万元，参加；

13.中国科学院STS项目，微藻中亚麻酸的提取及富集技术，2016-2017，42万元，参加；

14.特色所项目，梁子湖藻类研发基地试验平台建设，2015-2018，31万元，参加；

15.创新领域前沿项目，基因工程制备微藻生物柴油关键技术的研究，2010-2012，100万元，主持；

16.中科院创新领域前沿项目，中国科学院“百人计划”，2011-2013，260万元，主持；

17.企业委托，炼厂烟气高耐受性微藻选育与培养工艺的研究，2013-2014，100万元，主持

18.企业委托，“渔光一体”系列研究-草鱼养殖，养殖模式，理化因子，2015-2016，40万元，主持；

19.企业委托，产油微藻发酵培养工艺及藻油提取工艺的研究，2017，10万元，主持

【专利】

1.孙中亮；王强；周创创；陈辉。一种基于浊度值反馈补加硅酸盐培养硅藻的方法和装置。专利号：ZL202010876469.7

2.王强；陈为先。一种能去除高重金属含量水体中的重金属的小球藻W3及其应用。专利号：ZL201710909193.6

3.王强；陈辉；何晨柳；朱曦。一种使用尿素纯化藻油中的GLA的方法。专利号：ZL201711308785.9

4.王强；陈辉；何晨柳；汪杰；陈为先。能去除高重金属含量水体中的重金属的小球藻W5及应用。专利号:ZL2018 10469458.X

5.王强；陈辉。一种基于PEA荧光曲线测定水体初级生产力的方法。专利号：ZL201911406759.9

6.王强；陈辉；何晨柳；朱曦。一种使用固定化脂肪酶富集藻泊中的GLA的方法。专利号：ZL201711307487.8

7.王强；陈辉；何晨柳；汪杰；陈为先。能快速去除高重金属含量水体中重金属的小球藻W6及应用。专利号：ZL201810469459.4

8.王强；陈辉；何晨柳；汪杰；陈为先。能去除高重金属含量水体中的重金属的小球藻W2及应用。专利号：ZL201810468898.3

9.王强；陈为先。一种可同时积累油脂和分泌氨基酸的微藻及其应用。专利号：ZL201710661334.7

10.王强；陈为先。一种能产生虾青素的小球藻W7及其应用。专利号：ZL201810480849.1

11.王强；吴宗文；谢伟；陈辉；何晨柳；陈为先。一种测量Fo来估算水体的初级生产力的方法。ZL201610100962.3

12.王强；陈辉；何晨柳；乔亚琴。一种利用叶绿素荧光参数Fv/Fm确定产油微藻收获时间的方法。专利号：ZL201410629226.8

13.王强；陈辉；何晨柳。一种利用无机氮源的微藻光合兼养高密度发酵培养方法及应用。专利号：ZL201410063243.X

14.王强；陈辉；何晨柳。一种用于微藻培养的圆柱形气升式高效光生物反应器及应用。专利号：ZL201410063589.X

【教学及人才培养】

培养的研究生荣获包括研究生国家奖学金、中科院院长奖学金等奖项40余人次。

【主要荣誉】

2023年“河南大学文明教师”

2022年当选中国民主同盟河南省委副主委，并当选河南省政协委员。

获国务院“华创杯”三等奖、“中国产学研合作创新奖”、“中国化工学会科学技术奖”和“中国商业联合会科学技术奖”二等奖，先后两次获国际能源环境领域最高国际奖项“Eni Award”提名。