教师名录

【研究方向】

自组装人工酶构建与性能调控、纳米生物电化学及新型传感器、蛋白质聚集与保护机制、糖尿病等氧化应激相关疾病的跨学科研究

【办公地点】河南大学生命科学学院C512

【联系邮箱】hongjun@henu.edu.cn

【教育及工作经历】

1986-1991吉林大学 电子科学系 半导体化学 学士学位（学制5年)

1991-1994吉林大学 电子科学系 半导体材料 硕士学位(学制3年)

1994-1995广东 珠海银城微电子公司 电子产品设计研发

1995-1998郑州大学 物理工程学院 教师

1998-2000伊朗 德黑兰大学 访问学者

2000-2006伊朗 德黑兰大学 生物物理学 博士（博士后）

2008 -至今 河南大学 生命科学学院 教师

【代表性论文】

1. Mohammad Edrisi, Hossein Daneshgar, Navid Rabiee, Payam Arghavani, Faezeh Moosavi-Movahedi, Ashkan Zare Karizak, Ali Khatibi,Jun Hong, Mojtaba Bagherzadeh, Ali A. Moosavi-Movahedi. Doxorubicin bioavailability to human hemoglobin and cancer cells via MOF-A520.Journal of Molecular Liquids2024, 394, 123724.

2. Mehrnaz Hosseini Jafari, Mohammad Bagher Shahsavani, Masaru Hoshino,Jun Hong, Ali Akbar Saboury, Ali Akbar Moosavi-Movahedi, Reza Yousefi. Unveiling the structural and functional consequences of the p.D109G pathogenic mutation in human αB-Crystallin responsible for restrictive cardiomyopathy and skeletal myopathy.International Journal of Biological Macromolecules2024, 254, 127933.

3. Bao-Lin Xiao, Xin-Xin Ma, Yang-Yang Li,Jun Hong*, Ali Akbar Moosavi-Movahedi. Conformation and molecular dynamics simulation of the interaction between cytochrome c and DNA.Journal of the Iranian Chemical Society. 2023.https://doi.org/10.1007/s13738-023-02872-0.

4. Xin-Xin Ma, Yang-Yang Li, Xin-Yan Song, Ke-Xin Xu, Yu-Jie Chen, Xin Meng, Yu-Ying Li, Lin-Lin Ma, Ali Akbar Moosavi-Movahedi,Jun Hong*, Bao-Lin Xiao. Electrochemical Properties Analysis of Immobilized Glucose Oxidase on Multi-Walled Carbon Nanotubes and Hydroxy-Fullerene Nanocomposites.Journal of The Electrochemical Society. 2023, 170,075504.https://doi.org/10.1149/1945-7111/ace7fa.

5. Mona Nourazaran, Reza Yousefi, Faezeh Moosavi-Movahedi, Farhad Panahi,Jun Hong, Ali A. Moosavi-Movahedi, The structural and functional consequences of melatonin and serotonin on human αB-crystallin and their dual role in the eye lens transparency.BBA - Proteins and Proteomics, 2023, 1871, 140928.https://doi.org/10.1016/j.bbapap.2023.140928.

6. Yang-Yang Li, Xin-Xin Ma, Xin-Yan Song, Lin-Lin Ma, Yu-Ying Li, Xin Meng, Yu-Jie Chen, Ke-Xin Xu, Ali Akbar Moosavi-Movahedi, Bao-Lin Xiao,Jun Hong*, Glucose biosensor based on glucose oxidase immobilized on BSA cross-linked nanocomposite modified glassy carbon electrode.Sensors. 2023,23,3209.https://doi.org/10.3390/s23063209.

7. Somayyeh Ghareghomi, Faezeh Moosavi-Movahedi, Luciano Saso, Mehran Habibi-Rezaei, Ali Khatibi,Jun Hongand Ali A. Moosavi-Movahedi, Modulation of Nrf2/HO-1 by Natural Compounds in Lung Cancer.Antioxidants. 2023, 12, 735.https://doi.org/10.3390/antiox12030735.

8. Yuxiang Xu, Yongjie Li, Changqing Wang, Tingting Han, Haixuan Liu, Lin Sun,Jun Hong, Makoto Hashimoto and Jianshe Wei, The reciprocal interactions between microglia and T cells in Parkinson’s disease: a double-edged sword. Journal of Neuroinflammation 2023, 20, 33.https://doi.org/10.1186/s12974-023-02723-y.

9. Xin Meng, Bao-Lin Xiao, Xin-Yan Song, Xin-Xin Ma, Yang-Yang Li, Lin-Lin Ma, Yu-Jie Chen, Yu-Ying Li, Ke-Xin Xu, Jian-She Wei, Tao Hong, Ali Akbar Moosavi-Movahedi，Jun Hong*, Highly Selective and Sensitive Sensor Based IL and CMC-MWCNTs Nanocomposite for Rutin Determination.Chemosensors. 2023, 11, 171. https://doi.org/10.3390/chemosensors11030171.

10. Xin-Yan Song, Xin Meng, Bao-Lin Xiao, Yang-Yang Li, Xin-Xin Ma, Ali Akbar Moosavi-Movahedi，andJun Hong*, MWCNTs-CTAB and HFs-Lac Nanocomposite-Modified Glassy Carbon Electrode for Rutin Determination.Biosensors. 2022, 12, 632. https://doi.org/10.3390/bios12080632.

11. Nan-Nan Niu, Wen‑Jun Zhao, Bao‑Lin Xiao, Yu‑Chen Liang, Xin Meng, Xin‑Yan Song, Di Li,Jun Hong*, Ali Akbar Moosavi‑Movahedi. Quench treatment cytochrome c: Transformation from a classical redox protein to a peroxidase like enzyme.Journal of the Iranian Chemical Society. 2022, 19(6), 2347-2357. https://doi.org/10.1007/s13738-021-02451-1.

12. Wen-Jun Zhao, Bao-Lin Xiao, Xin-Yan Song, Xin Meng, Xin-Xin Ma, Yang-Yang Li,Jun Hong* and Ali Akbar Moosavi-Movahedi.A Highly Sensitive Electrochemical Sensor Based on β-cyclodextrin Functionalized Multiwall Carbon Nanotubes and Fe₃O₄Nanoparticles for Rutin.Journal of the Electrochemical Society, 2022, 169, 047509.https://doi.org/10.1149/1945-7111/ac61bf.

13. Hoda Keshmiri Neghab, Mohammad Hasan Soheilifar, Ali Akbar Saboury, Bahram Goliaei,Jun Hong, Gholamreza Esmaeeli Djavid. Optogenetic Stimulation of Primary Cardiomyocytes Expressing ChR2.Journal of Lasers in Medical Sciences,2021, 12, e32.

14. Majid Sharifi, Abdulkarim Yasin Karim, Nadir Mustafa Qadir Nanakali, Abbas Salihi, Falah Mohammad Aziz,Jun Hong, Rizwan Hasan Khan, Ali Akbar Saboury, Anwarul Hasan, Osama K. Abou-Zied & Mojtaba Falahati. Strategies of enzyme immobilization on nanomatrix supports and their intracellular delivery.Journal of Biomolecular Structure and Dynamics.2020,38(9), 2746-2762.

15. Hoda Keshmiri Neghab, Bahram Goliaei, Ali A. Saboury, Gholamreza Esmaeeli Djavid, Majid Pornour,Jun Hong, Michael Grusch, Modulation of cardiac optogenetics by vitamin A.Biofactors.2019, 45:983-990.

16. Bao-Lin Xiao, Yan-Na Ning, Nan-Nan, Niu, Di Li, Ali Akbar Moosavi-Movahedi, Nader Sheibani,Jun Hong*. Steered molecular dynamic simulations of conformational lock of Cu,Zn-superoxide dismutase.Scientific Reports.2019, 9, 4353.

17. Yan-Na Ning, Bao-Lin Xiao, Nan-Nao Niu, Ali Akbar Moosavi-Movahedi,Jun Hong*, Glucose Oxidase Immobilized on a Functional Polymer Modified Glassy Carbon Electrode and Its Molecule Recognition of Glucose.Polymers.2019, 11, 115.

18. Di Li, Xiao-Lu Yang, Bao-Lin Xiao, Fang-Yong Geng,Jun Hong*, Nader Sheibani, Ali Akbar Moosavi-Movahedi. Detection of Guanine and Adenine Using an Aminated Reduced Graphene Oxide Functional Membrane-Modified Glassy Carbon Electrode.Sensors.2017, 17, 1652.

19. Di Li, Xiao-Yu Zhang, Bao-Lin Xiao,Jun Hong*, Ali Akbar Moosavi-Movahedi. Direct electrochemistry of glucose oxidase immobilized on a hydroxyl fullerenes-TiO₂nanocomposite modified glassy carbon electrode. 2^ndInternational Conference on Biomedical and biological Engineering (BBE2017),Advances in Biological Sciences Research(ABSR) volume 4, 331-336.

20. Di Li, Yu-Shuai Zhang, Fang-Yong Geng, Bao-Lin Xiao,Jun Hong*, Tao Hong. Electrochemical Study on A Heme-Histidine-Sodium Decyl Sulfate Nano Micelles Complex Artificial Peroxidase. International Conference on Biological Engineering and Pharmacy (BEP2016),Advances in Biological Sciences Research(ABSR) volume 3, 95-99.

21. Fang-Yong Geng, Di Li, Yun-Fei Gao, Bao-Lin Xiao,Jun Hong*, Ali Akbar Moosavi-Movahedi. A Sensitive and Reproducible Spectrophotometric Assay for Glucose Oxidase Activity and Its Application in Conformational Lock. International Conference on Biological Engineering and Pharmacy (BEP2016),Advances in Biological Sciences Research(ABSR) volume 3, 88-94.

22. Xiao-Lu Yang, Yu-Shuai Zhang, Tian Yang, Fang-Yong Geng, Di Li, Bao-Lin Xiao,Jun Hong*, Ali Akbar Moosavi-Movahedi, Hedayatollah Ghourchian. A soft-template nanostructured peroxidase based on cytochrome c and sodium decyl sulfate and its electrochemical properties on hydroxyl fullerenes modified glassy carbon electrode.Journal of the Iranian Chemical Society.2016, 13, 471-479.

23. Tian Yang, Yu-Shuai Zhang, Xiao-Lu Yang, Fang-Yong Geng, Bao-Lin Xiao, Meng-Meng Xu, Di Li,Jun Hong*and Ali Akbar Moosavi-Movahedi.A novel self-assembled nano micelle as a highly efficient artificial peroxidase based on hexadecyl trimethyl ammonium bromide and cytochrome c.Bio-Medical Materials and Engineering.2015, 26, S73–S79.

24. Zainab Moosavi-Movahedi, Hussein Gharibi, Hamid Hadi-Alijanvand, Mohammad Akbarzadeh, Mansoore Esmaili, Maliheh S. Atri, Yahya Sefidbakht, Mousa Bohlooli, Khodadad Nazari, Soheila Javadian,Jun Hong,Ali A. Saboury, Nader Sheibani, Ali A. Moosavi-Movahedi. Caseoperoxidase, Mixed β-Casein-SDS-Hemin-Imidazole Complex: A Nano Artificial Enzyme.Journal of Biomolecular Structure and Dynamics.2015, 33, 2619-2632.

25. Mina Naderi, Ali A. Moosavi-Movahedi, Saman Hosseinkhani, Mahboobeh Nazari, Mousa Bohlooli,Jun Hong, Hamid Hadi-Alijanvand6 and Nader Sheibani. Implication of Disulfide Bridge Induced Thermal Reversibility, Structural and Functional Stability for Luciferase.Protein and Peptide Letters.2015, 22, 23-30.

26. Tian Yang, Xiao-Lu Yang, Yu-Shuai Zhang, Bao-Lin Xiao andJun Hong*. Glucose Biosensing Using Glassy Carbon Electrode Modified with Polyhydroxy-C60, Glucose Oxidase and Ionic-liquid.Bio-Medical Materials and Engineering.2014,24,2197–2202.

27. Yun-Fei Gao, Tian Yang, Xiao-Lu Yang, Yu-Shuai Zhang, Bao-Lin Xiao,Jun Hong*, Nader Sheibani, Hedayatollah Ghourchian, Tao Hong, Ali Akbar Moosavi-Movahedi. Direct electrochemistry of glucose oxidase and glucose biosensing on a hydroxyl fullerenes modified glassy carbon electrode.Biosensors and Bioelectronics.2014, 60, 30-34.

28. Yun-Fei Gao, Ying-Xue Zhao, Tian Yang, Bao-Lin Xiao, Yu-Shuai Zhang, Xiao-Lu Yang,Jun Hong*, Hedayatollah Ghourchian, Nader Sheibani, Ali Akbar Moosavi-Movahedi. A nano self-assembled artificial peroxidase: spectroscopic and electrochemical investigations.Journal of the Iranian Chemical Society.2014, 11, 1397-1405.

29. Shohreh Ariaeenejad, Ali A. Moosavi-Movahedi, Kaveh Kavousi, Mohammad Reza Dayer,Jun Hong, RezaYousefi, Nader Sheibani and Mehran Habibi-Rezaei. The Species and Heme Pocket Properties of Sturgeon Hemoglobins Upon Interaction with N-dodecyl Trimethylammonium Bromide.Protein and Peptide Letters.2014, 21, 171-178.

30. Bao-Lin Xiao,Jun Hong*, Yun-Fei Gao, Tian Yang, Ali Akbar Moosavi-Movahedi, Hedayatollah Ghourchian. Direct electron transfer of horseradish peroxidase on a functional nanocomplex modified glassy carbon electrode.Bio-Medical Materials and Engineering.2014, 24, 1079–1084.

31. M. Bohlooli, A.A. Moosavi-Movahedi, F. Taghavi, P. Maghami, A.A. Saboury, Z. Moosavi-Movahedi, M. Farhadi,J. Hong, N. Sheibani, M. Habibi-Rezaei. Investigation of thermal reversibility and stability of glycated human serum albumin.International Journal of Biological Macromolecules.2013, 62, 358–364.

32. Jun Hong*, Wei-Yun Yang, Ying-Xue Zhao, Bao-Lin Xiao, Yun-Fei Gao, Tian Yang, Hedayatollah Ghourchian, Zainab Moosavi-Movahedi, Nader Sheibani, Jian-Guo Li, Ali Akbar Moosavi-Movahedi. Catalase immobilized on a functionalized multi-walled carbon nanotubes-gold nanocomposite as a highly sensitive bio-sensing system for detection of hydrogen peroxide.Electrochimica Acta.2013, 89,317-325.

33. Jun Hong*, Ying-Xue Zhao, Bao-Lin Xiao, Ali Akbar Moosavi-Movahedi, Hedayatollah Ghourchian, Nader Sheibani. Direct electrochemistry of hemoglobin immobilized on a functionalized multi-walled carbon nanotubes and gold nanoparticles nanocomplex-modified glassy carbon electrode.Sensors.2013, 13, 8595-8611.

34. Wei-Yun Yang,Jun Hong*, Ying-Xue Zhao, Bao-Lin Xiao, Yun-Fei Gao, Tian Yang, Ali Akbar Moosavi-Movahedi, Hedayatollah Ghourchian and Zainab Moosavi-Movahedi, Electrochemical Study of a Nano Vesicular Artificial Peroxidase on a Functional Nano Complex Modified Glassy Carbon Electrode.Journal of New Materials for Electrochemical Systems. 2013, 16(2),89-95.

35. Shohreh Ariaeenejad, Mehran Habibi-Rezaei, Kaveh Kavousi, Shahla Jamili , Mohammad Reza Fatemi,Jun Hong, Najmeh Poursasan, Nader Sheibani, Ali. A. Moosavi-Movahedi. Denaturation and intermediates study of two sturgeon hemoglobins by n-dodecyl trimethylammonium bromide.International Journal of Biological Macromolecules.2013, 53,107-113.

36. Jun Hong*, Wei Wang, Kun Huang, Wei-Yun Yang, Ying-Xue Zhao, Bao-Lin Xiao, Yun-Fei Gao, Zainab Moosavi-Movahedi, Shahin Ahmadian, Mousa Bohlooli, Ali Akbar Saboury, Hedayatollah Ghourchian, Nader Sheibani, Ali Akbar Moosavi-Movahedi. A self-assembled nano-cluster complex based on cytochrome c and nafion: An efficient nanostructured peroxidase.Biochemical Engineering Journal.2012, 65, 16-22.

37. Jun Hong*, Wei Wang, Kun Huang, Wei-Yun Yang, Ying-Xue Zhao, Bao-Lin Xiao, Yun-Fei Gao, Zainab Moosavi-Movahedi, Hedayatollah Ghourchian, Ali Akbar Moosavi-Movahedi. A Highly Efficient Nano-Cluster Artificial Peroxidase and Its Direct Electrochemistry on Nano Complex Modified Glassy Carbon Electrode.Analytical Sciences.2012, 28, 711-716.

38. Jun Hong*, Kun Huang, Wei Wang, Wei-Yun Yang, Ying-Xue Zhao, Bao-Lin Xiao, Zainab Moosavi-Movahedi, Hedayatollah Ghourchian, Mousa Bohlooli, Nader Sheibani, Ali Akbar Moosavi-Movahedi. Cytochrome c embraced in sodium dodecyl sulfate nano-micelle as a homogeneous nanostructured peroxidase.Journal of the Iranian Chemistry Society.2012, 9, 775-782.

39. Jun Hong*, Kun Huang, Wei Wang, Wei-Yun Yang, Ying-Xue Zhao, Bao-Lin Xiao, Zainab Moosavi-Movahedi, Hedayatollah Ghourchian, Ali Akbar Moosavi-Movahedi. Direct Electrochemistry of Artificial Peroxidase Based on Self-Assembled Cytochrome c-SDS-nano-micelle.Analytical Letters. 2012,45, 2221-2235.

40. 王玮,洪军*,黄琨,杨卫云,赵莹雪,高云飞,肖保林.自组装纳米簇模拟过氧化物酶：光谱及电化学研究.分析化学.2012, 40, 1543-1548。

41. 黄琨,洪军*,王玮,肖保林,杨卫云,赵莹雪,高云飞.十二烷基磺酸钠纳米胶团-细胞色素c自组装高效纳米结构过氧化物酶.生物物理学报.2012, 28, 771-781.

42. Farzaneh Farivar, Ali Akbar Moosavi-Movahedi, Yahya Sefidbakht, Khodadad Nazari,Jun Hong, Nader Sheibani. Cytochrome c in sodium dodecyl sulfate reverse micelle nanocage: From a classic electron carrier protein to an artificial peroxidase enzyme.Biochemical Engineering Journal.2010, 49, 89–94.

43. Jalil Badraghi, Ali Akbar Moosavi-Movahedi, Ali Akbar Saboury, Reza Yousefi, Ahmad Sharifzadeh,Jun Hong,Thomas Haertlé, Amir Niasari-Naslaji, Nader Sheibani. Dual behavior of sodium dodecyl sulfate as enhancer or suppressor of insulin aggregation and chaperone-like activity of camel alpha-S1-casein.International Journal of Biological Macromolecules.2009, 45, 511–517.

44. A.A. Moosavi-Movahedi, F. Semsarha, H. Heli, K. Nazari, H. Ghourchian,J. Hong, G.H. Hakimelahi, A.A. Saboury and Y. Sefidbakht. Micellar histidinate hematin complex as an artificial peroxidase enzyme model: Voltammetric and spectroscopic investigations.Colloids and Surfaces A: Physicochem. Eng. Aspects.2008,320,213-221.

45. Jun Hong, Ali Akbar Moosavi-Movahedi, Hedayatollah Ghourchian, Ahmad Molaei Rad, Saeed Rezaei-Zarchi. Direct electron transfer of horseradish peroxidase on Nafion-cysteine modified gold electrode.Electrochemica Acta. 2007, 52, 6261–6267.

46. Jun Hong, Hedayatollah Ghourchian, Saeed Rezaei-zarchi, Ali Akbar Moosavi-Movahedi, Shahin Ahmadian, Ali Akbar Saboury.Nafion-Methylene Blue Functional Membrane and its Application in Chemical and Biosensing.Analytical Letters.2007, 40, 483-496.

47. Saeed Rezaei-Zarchi, Ali Akbar Saboury,Jun Hong, Hedayatollah Ghourchian, Parviz Norouzi, Ali Akbar Moosavi-Movahedi, Mohammad Reza Ganjali, and Aisha Javed. A new method for determination of hemoglobin concentration by using bromide-modified silver electrode.Biotechnology and Applied Biochemistry.2007,47,153-158.

48. S. Rezaei-Zarchi, A. A. Saboury,J. Hong, P. Norouzi, A. B. Moghaddam, H. Ghourchian,M. R. Ganjali, A. A. Moosavi-Movahedi, A. Javed, and A. Mohammadian. Electrochemical Behavior of Redox Proteins Immobilized on Nafion-Riboflavin Modified Gold Electrode.Bulletin of Korean Chemical Society. 2007,28,2266-2270.

49. Saeed Rezaei-Zarchi, Ali Akbar Saboury, Parviz Norouzi,Jun Hong, Shahin Ahmadian, Mohammad Reza Ganjali, Ali Akbar Moosavi-Movahedi, Abdolmajid Bayandori Moghaddam, Aisha Javed. Use of silver nanoparticles as an electron transfer facilitator in electrochemical ligand-binding of haemoglobin.Journal of Applied Electrochemistry. 2007,31,1021-1026.

50. A. Molaei Rad, H. Ghourchian, A.A. Moosavi-Movahedi,J. Hong, K. Nazari.Spectrophotometric assay for horseradish peroxidase activity based on pyrocatechol-aniline coupling hydrogen donor.Analytical Biochemistry.2007, 362, 38-43.

51. Saeed Rezaei-Zarchi, Ali Akbar Saboury, Parviz Norouzi,Jun Hong, Abolfazl Barzegar, Mohammad Reza Ganjali, Hedayatollah Ghourchian, Ali Akbar Moosavi-Movahedi, Aisha Javed and Abbas Ali Rostami. Electrochemical Recognition of Metalloproteins by Bromide-modified Silver Electrode - A New Method.International Journal of Molecular Sciences.2007,8, 723-735.

52. S. Rezaei-Zarchi, A.A. Saboury, H.Ghourchian,J. Hong, A.Barzegar, P. Norouzi, A.A. Moosavi-Movahedi, M. R. Ganjali and A. Javed. Electrochemical investigation of the effect of some organic phosphates on haemoglobin.Journal of Biosciences.2007, 32, 271-278.

53. A. Molaei Rad, A. Akbar Moosavi-Movahedi, Hedayatollah Ghourchian, Nasser Safari,Jun Hong, Zinab Moosavi-Movahedi, Khodadad Nazari, A. Akbar Saboury and P. Rajabali Jamaat Effects of substituted metal-free porphyrins in apo-horseradish peroxidase.Journal of Porphyrins and Phthalocyanines.2007,11,836-845.

54. Jun Hong, Hedayatollah Ghourchian, Ali Akbar Moosavi–Movahedi. Direct electron transfer of redox proteins on a Nafion-cysteine modified gold electrode.Electrochemistry Communications.2006, 8, 1572–1576.

55. J．Hong, A. A. Moosavi-Movahedi, H. Ghourchian, M. Amani, M. Amanlou, F.C. Chilaka. Thermal Dissociation and conformational lock of bovine superoxide dismutase.Journal of Biochemistry and Molecular Biology.2005, 38, 533-538.

    【项目/著作/专利】

    洪军，李迪，肖保林,一种利用细胞色素C自组装过氧化物酶测定表面活性剂临界胶束浓度的方法,专利号：ZL2016100010642授权公告日：2019年3月22日

    【教学及人才培养】

    讲授本科生课程《生物仪器分析》、《生物物理学》，研究生课程《生物学研究方法与学术规范》、《分子生物物理学》等。